CYBERnano has worked on different projects related to the optimization of quality and productivity in biomanufacturing processes. In each project, CYBERnano is implementing a data-driven modeling approach based on design of experiments and efficient data analysis tools. The same approach was also applied on the optimization of therapeutic schemes to control the benefice-risk balance.
Exemple of results for the optimization of an extraction process. Trois facteur de production ont été testés: durée, température et ratio. Les courbes de niveau représentent une réponse liée à la quantité de produit récupéré.
Example of results for the optimization of an anticancer treatment. Three therapeutic factors were tested and two response were analyzed.
 L. Tirand, T. Bastogne, D. Bechet, M. Linder, N. Thomas, C. Frochot, F. Guillemin, and M. Barberi- Heyob, “Response surface methodology: an extensive potential to optimize photodynamic therapy condi- tions in vivo,” International Journal of Radiation Oncology, Biology, Physics, vol. 75, no. 1, pp. 244–252, 2009.
 T. Bastogne, A. Richard, P. Sibille, and E. Bichon, “Optimized multivariable control of an industrial cement milling circuit,” in Proc. of the 3rd European Control Conference, vol. 4, (Roma, Italy), pp. 3098– 3104, September 1995.